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Creatinine clearance
A direct estimate of glomerular filtration from a 24-hour urine collection plus one blood sample.
Other names: Creatinine clearance, CrClSection: Urine tests
Updated: August 31, 2026·MedProtect editorial team Reference information — not a diagnosis or a prescription
In shortCreatinine clearance estimates how much blood the kidneys filter per minute. Typical references are 97–137 mL/min for men and 88–128 mL/min for women. It requires a complete 24-hour urine collection and a blood creatinine measurement.
Reference ranges
Group
Reference range
Men — typical range (international reference, not a national standard)
97–137 mL/min
Women — typical range (international reference, not a national standard)
88–128 mL/min
Values from the MedlinePlus Medical Encyclopedia (international reference, not a national standard). Values decline with age. Reference ranges vary between laboratories and assays — use the range printed on your own lab report.
Check your value
Enter the number from your lab report — see how it compares with the typical range. Mind the units shown in the chosen row.
A rough comparison with a typical range, not a diagnosis. Reference ranges vary between laboratories — check the range on your own report and let a clinician interpret the result.
What this marker is
Creatinine is produced by muscles at a steady rate and filtered by the kidneys. Comparing its amount in daily urine with its blood level approximates the glomerular filtration rate.
The test is used when an accurate GFR matters — dosing of kidney-cleared drugs, assessing kidney donors — though in routine practice a calculated eGFR from blood often suffices.
When it is high
Early diabetes and pregnancyFiltration can be temporarily increased; large muscle mass also raises creatinine generation.
When it is low
Reduced kidney functionA falling clearance reflects declining filtration — interpreted with blood creatinine and eGFR.
What can skew the result
These factors can shift the value without any disease — worth considering before a retest:
Completeness of urine collectionVigorous exerciseHeavy meat intake beforehandSome medicines
How to prepare
A full 24-hour urine collection; blood is drawn during the same period. Intense exercise and heavy meat meals are avoided beforehand.
When a retest makes sense
If collection completeness is doubtful, the test is repeated; often the provider relies on a calculated eGFR instead.
Who usually reviews this result
A result outside the reference range is usually reviewed by: your GP or primary care doctor; a nephrologist for reduced filtration. Bring your lab report and any previous results to the appointment.
Names used on lab reports
Your report may use any of these names: Creatinine clearanceCrClRehberg test
Units
Measured in: mL/min
Several markers on your report?
See how MedProtect explains results in the app: the whole report, a check of the recognized values, and a clear breakdown.
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