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24-hour urine protein
The total protein excreted in urine over 24 hours — a measure of kidney filter damage and of treatment effect.
Other names: 24-hour proteinuria, total urine proteinSection: Urine tests
Updated: August 31, 2026·MedProtect editorial team Reference information — not a diagnosis or a prescription
In shortThe 24-hour urine protein quantifies daily protein loss. Normal is below 100 mg per day. It grades the severity of kidney disease and tracks treatment; accuracy depends on collecting the full 24-hour volume.
Reference ranges
Group
Reference range
Total protein — typical range (international reference, not a national standard)
< 100 mg/day
Value from the MedlinePlus Medical Encyclopedia (international reference, not a national standard). Many laboratories quote up to 150 mg/day — the report's reference applies.
Check your value
Enter the number from your lab report — see how it compares with the typical range. Mind the units shown in the chosen row.
A rough comparison with a typical range, not a diagnosis. Reference ranges vary between laboratories — check the range on your own report and let a clinician interpret the result.
What this marker is
Healthy kidneys lose only trace protein. Persistent loss above normal indicates damage to the kidney filter; the amount correlates with severity and prognosis.
Collection starts after discarding the first morning urine and includes every void for the next 24 hours, ending with a final morning void; missed portions invalidate the result.
When it is high
Glomerular diseaseNephrotic-range losses occur in glomerulonephritis and diabetic nephropathy.
PreeclampsiaIn pregnancy, rising proteinuria with hypertension is a warning sign.
Orthostatic proteinuriaBenign upright-related loss in young people, confirmed by split day/night collections.
When it is low
Expected findingMinimal daily protein loss is normal.
What can skew the result
These factors can shift the value without any disease — worth considering before a retest:
Completeness of the 24-hour collectionExercise and feverProlonged standing
How to prepare
A full 24-hour collection in the provided container, kept cool; the first morning urine is discarded, the last is included.
When a retest makes sense
If collection completeness is doubtful, the collection is repeated; otherwise on the nephrologist's schedule.
Who usually reviews this result
A result outside the reference range is usually reviewed by: your GP or primary care doctor; a nephrologist for persistent proteinuria. Bring your lab report and any previous results to the appointment.
Names used on lab reports
Your report may use any of these names: 24-hour urine proteinTotal urine protein24-hour proteinuria
Units
Measured in: mg/day
Several markers on your report?
See how MedProtect explains results in the app: the whole report, a check of the recognized values, and a clear breakdown.
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