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Fructosamine
Glycated serum proteins — the average glucose of the last 2–3 weeks. Complements HbA1c when it is uninformative.
Other names: Fructosamine, glycated serum proteinSection: Blood chemistry
Updated: August 31, 2026·MedProtect editorial team Reference information — not a diagnosis or a prescription
In shortFructosamine reflects average glucose over the previous 2–3 weeks, shorter than the 2–3 months of HbA1c. A typical reference for people without diabetes is 205–285 micromoles per liter (µmol/L). It is used in pregnancy, anemia, hemoglobinopathies, and after recent treatment changes.
Reference ranges
Group
Reference range
Adults without diabetes — typical range (international reference, not a national standard)
205–285 micromoles per liter (µmol/L)
Range from the Severn Pathology test directory, NHS (international reference, not a national standard). Treatment targets in diabetes are set by the provider. Reference ranges vary between laboratories and assays — use the range printed on your own lab report.
Check your value
Enter your result — we will show how it compares with a typical range. Match the units of the selected row.
Approximate comparison with a typical range, not a diagnosis. Reference intervals vary by laboratory and method — check your report; result interpretation is done by a doctor.
What this marker is
Glucose binds irreversibly to serum proteins, mostly albumin. Because albumin lives 2–3 weeks, fructosamine answers a short-window question: how has glucose control been lately?
The test shines where HbA1c fails — anemia, hemoglobin variants, recent blood loss, pregnancy — and when therapy has just changed and a faster readout is needed.
When it is high
Worsening glucose controlA rise reflects higher average glucose over the last 2–3 weeks.
Gestational diabetesIn pregnancy the test helps assess control quickly.
When it is low
Low serum albuminNephrotic syndrome and severe liver disease lower the result independently of glucose.
What can skew the result
These factors can shift the value without any disease — worth considering before a retest:
Serum albumin levelHigh-dose vitamin CRecent changes in diabetes treatment
How to prepare
Fasting is not required; the albumin level is considered in interpretation.
When a retest makes sense
When diabetes therapy is adjusted — after 2–3 weeks; trends are compared within one laboratory.
Who usually reviews this result
A result outside the reference range is usually reviewed by: an endocrinologist; your GP or primary care doctor. Bring your lab report and any previous results to the appointment.
Names used on lab reports
Your report may use any of these names: FructosamineGlycated serum proteinGlycated albumin (related test)
Units
Measured in: µmol/L
µmol/L=mmol/L
mmol/L = µmol/L × 0.001
Several markers on your report?
See how MedProtect explains results in the app: the whole report, a check of the recognized values, and a clear breakdown.
HbA1c is glucose on hemoglobin (red cells live about 3 months); fructosamine is glucose on serum proteins (about 3 weeks). Fructosamine reacts faster to treatment changes.
When is HbA1c unsuitable?
With anemia, hemoglobinopathies, recent blood loss, and pregnancy — then fructosamine or glycated albumin is used.
Does vitamin C interfere?
High doses of ascorbate can distort some methods — supplement use is reported to the provider.
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