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Proteína total

La albúmina y globulina combinadas en suero sanguíneo; una ventana a la nutrición, hígado y riñones.

Otros nombres:Total serum protein Sección:Química sanguínea
En resumenThe normal range is 6.5–8.1 g/dL (65–81 g/L). Low values point to nutrition, liver, or kidney problems; high values to inflammation or blood cancers.

Valores de referencia

GrupoValor de referencia
Adultos6.5–8.1 g/dL (65–81 g/L)
Normal value ranges vary slightly among laboratories. Total protein measurements may be increased during pregnancy.

Compruebe su valor

Enter the number from your lab report — see how it compares with the typical range. Mind the units shown in the chosen row.

A rough comparison with a typical range, not a diagnosis. Reference ranges vary between laboratories — check the range on your own report and let a clinician interpret the result.

Qué es este marcador

The total protein test measures the combined amount of two classes of proteins in the fluid portion of the blood: albumin and globulins. Albumin keeps fluid from leaking out of blood vessels and carries chemicals through the blood; globulins are an important part of the immune system. Proteins are essential parts of all cells and tissues.

The test is often done to investigate nutritional problems, kidney disease, or liver disease, and the report usually comes with the albumin-to-globulin (A/G) ratio. A low A/G ratio can be caused by autoimmune disease such as lupus, by liver disease including cirrhosis, or by kidney disease; a high ratio can accompany certain genetic disorders or leukemia.

If total protein is abnormal, more tests follow to find the exact cause — the total value shows that something is off, but not which protein class is responsible. Protein electrophoresis is the test that separates the classes in detail.

Blood is drawn from a vein, usually from the inside of the elbow or the back of the hand. Many medicines can interfere with the result, so bring the full list of what you take; your provider will say if anything should be paused.

Cuando está elevado

Chronic inflammation or infectionLong-running inflammatory and infectious diseases — including HIV and hepatitis B or C — raise the globulin fraction and with it the total.
Multiple myelomaThis blood cancer produces large amounts of a single antibody protein, pushing total protein up.
Waldenström diseaseAnother condition of abnormal antibody production that increases total protein.

Cuando está bajo

Enfermedad hepáticaThe liver makes albumin and many other blood proteins, so liver disease lowers the total.
Kidney protein lossNephrotic syndrome and glomerulonephritis let protein escape into the urine; bleeding (hemorrhage) and extensive burns lose protein directly.
Malnutrition and malabsorptionWhen the body does not get or cannot absorb enough protein — including protein-losing enteropathy — there is too little raw material to maintain blood protein.
AgammaglobulinemiaA shortage of antibody-producing capacity lowers the globulin fraction.

Qué puede alterar el resultado

Estos factores pueden alterar el valor sin ninguna enfermedad — vale la pena considerarlos antes de repetir la prueba:

Pregnancy (can raise the measurement)Many medicines

Cómo prepararse

Many medicines can interfere with the result. Your provider will tell you if any medicine should be paused before the test; do not stop or change medicines on your own.

Cuándo tiene sentido repetir la prueba

An abnormal total is followed by tests that find the exact cause — typically the albumin and globulin split with the A/G ratio, and protein electrophoresis when a closer look is needed.

Quién suele revisar este resultado

Un resultado fuera del rango de referencia suele ser revisado por:your GP or primary care doctor; a gastroenterologist or nephrologist depending on the suspected cause. Traiga su informe de laboratorio y cualquier resultado anterior a la cita.

Nombres usados en los informes de laboratorio

Su informe puede usar cualquiera de estos nombres:
Proteína totalTotal serum proteinTPTotal protein with A/G ratio

Unidades y conversión

Medido en:g/dL

g/dL = g/L
g/dL × 10 = g/L. Example: 7.0 g/dL = 70 g/L. Results are rounded to 2 decimal places.

¿Varios marcadores en su informe?

See how MedProtect explains results in the app: the whole report, a check of the recognized values, and a clear breakdown.

Preguntas frecuentes

What is the A/G ratio?
The albumin-to-globulin ratio compares the two protein classes. A low ratio can come from autoimmune disease such as lupus, liver disease including cirrhosis, or kidney disease; a high ratio can accompany certain genetic disorders or leukemia.
Can pregnancy change the result?
Yes. Total protein measurements may be increased during pregnancy, so the stage of life matters when the number is read.
Does a low total protein mean I eat too little protein?
Not necessarily. Malnutrition is one cause, but liver disease, kidney protein loss, bleeding, burns, and malabsorption also lower the total. The follow-up tests separate them.

Fuentes

  1. Total Protein and Albumin/Globulin (A/G) Ratio: MedlinePlus Medical Test— MedlinePlus, Biblioteca Nacional de Medicina. Consultado: 29 de agosto de 2026.
  2. Total protein: MedlinePlus Medical Encyclopedia— MedlinePlus, Biblioteca Nacional de Medicina. Consultado: 29 de agosto de 2026.

Ver también